Handbook of Harnessing Biomaterials in Nanomedicine - Preparation, Toxicity and Applications
by Dan Peer (Tel Aviv University, Israel)
Hardback 432 pages 2012-01-31 Print ISBN: 9789814316460 eBook ISBN: 9789814364270 DOI: 10.4032/9789814364270
List price : $199.95
"The nanomedicine revolution has begun. To date, nearly 30 nanotechnology-based products have been approved for clinical use, including liposomal formulations and stealth polymer–drug conjugates. Importantly, the application of nanotechnology to medicine will continue to progressively and fundamentally change the landscape for the pharmaceutical and biotechnology industries. Dan Peer has done an exceptional job bringing together the world’s leading experts to provide an authoritative compilation covering the essential fundamentals and state-of-the-art approaches. The book includes essential methods for preparing nanomaterials, testing the function, and analyzing their safety with relevance to potential regulatory hurdles that may be encountered. This book will undoubtedly become an essential reference for scientists and technologists who aim to characterize, study, and develop clinically relevant and safe nanomedicines."
Prof. Jeffrey M. Karp - Harvard Stem Cell Institute, USA
"This book is a compendium of recent developments in nanomedicine and advanced drug delivery systems that highlight leading laboratories’ key findings on nanomaterial design, selection, and adverse effects. It is a valuable reference for both students and researchers."
Prof. S. Moein Moghimi - University of Copenhagen, Denmark
Nanomedicine has emerged as a novel field in medicine integrating nano-scale technologies with materials sciences, chemistry and biology. The medical application of nanotechnology has the potential to revolutionize diagnosis and therapy and bring this new field from a notion into reality while impacting the lives of millions around the world.
This book compiles and details cutting-edge research in science and medicine from the interdisciplinary standpoint who are currently revolutionizing drug delivery techniques through the development of nanomedicines. Edited by Dan Peer, a prominent bio-nanotechnologiest, this book will attract anyone involved materials sciences, chemistry, biology and medicine that would like to design applications in the medical field of nanotechnology towards cancer therapy, inflammation, viral infection, imaging and toxicity.
|1||Chapter 1: Biomaterial-Based Particulate Drug Carriers|
|21||Chapter 2: Single-Chain Polymer Nanoparticles for Application in Nanomedicine|
Ibon Odriozola, Miren Karmele Aiertza, Germán Cabañero, Hans-Jürgen Grande, and Iraida Loinaz
|43||Chapter 3: Polyethylene Glycol Polyester Block Copolymers: Biocompatible Carriers for Nanoparticulate Drug Delivery|
David S. Hart, Yunqi Zhao, and M. Laird Forrest
|77||Chapter 4: Recent Progress in Polymer Therapeutics as Nanomedicines|
Hemda Baabur-Cohen, Liora Omer, and Ronit Satchi-Fainaro
|123||Chapter 5: Polysaccharides as Nanomaterials for Therapeutics|
Shoshy Mizrahy and Dan Peer
|163||Chapter 6: RNAi as New Class of Nanomedicines|
Monika Dominska and Derek M. Dykxhoorn
|199||Chapter 7: Novel RNA Interference (RNAi)-Based Nanomedicines for Treating Viral Infections|
Nyree Maes, Skye Zeller, and Priti Kumar
|241||Chapter 8: Detection and Description of Tissue Disease: Advances in the Use of Nanomedicine for Medical Imaging|
Jason L.J. Dearling and Alan B. Packard
|261||Chapter 9: Image-Based High-Content Analysis, Stem Cells and Nanomedicines: A Novel Strategy for Drug Discovery|
Leonardo J. Solmesky, Yonatan Adalist, and Miguel Weil
|283||Chapter 10: Wrong Resemblance? Role of the Immune System in the Biocompatibility of Nanostructured Materials|
|309||Chapter 11: Complement Activation, Immunogenicity, and Immune Suppression as Potential Side Effects of Liposomes|
Janos Szebeni and Yechezkel (Chezy) Barenholz
|335||Chapter 12: Doxil® — The First FDA-Approved Nano-Drug: From an Idea to a Product|
Yechezkel (Chezy) Barenholz
Advanced undergraduate-and graduate-level students in nanotechnology; researchers in macromolecular science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in drug delivery; cancer therapy, inflammation, RNAi, imaging with nanocarriers, and immuno-nanotoxicity.
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