by Bin Wang (Marshall University, USA)
Hardback 450 pages 2014-02-28 Print ISBN: 9789814411646 eBook ISBN: 9789814411653 DOI: 10.4032/9789814411653
List price : $149.95
In the past few decades there has been incredible growth in “bionano”-related research, which has been accompanied by numerous publications in this field. Although various compilations address topics related to deoxyribonucleic acid (DNA) and protein, there are few books that focus on determining the structure of ribonucleic acid (RNA) and using RNA as building blocks to construct nanoarchitectures for biomedical and healthcare applications.
RNA Nanotechnology is a comprehensive volume that details both the traditional approaches and the latest developments in the field of RNA-related technology. This book targets a wide audience: a broad introduction provides a solid academic background for students, researchers, and scientists who are unfamiliar with the subject, while the in-depth descriptions and discussions are useful for advanced professionals.
The book opens with reviews on the basic aspects of RNA biology, computational approaches for predicting RNA structures, and traditional and emerging experimental approaches for probing RNA structures. This section is followed by explorations of the latest research and discoveries in RNA nanotechnology, including the design and construction of RNA-based nanostructures. The final segment of the book includes descriptions and discussions of the potential biological and therapeutic applications of small RNA molecules, such as small/short interfering RNAs (siRNAs), microRNAs (miRNAs), RNA aptamers, and ribozymes.
|1||Chapter 1: Introduction|
|5||Chapter 2: Fundamental Aspects of RNA|
|21||Chapter 3: Computational Methods for RNA Structure Prediction and Analysis|
David Dufour, Emidio Capriotti, and Marc A. Marti-Renom
|51||Chapter 4: Computational Modeling for RNA Structure Discovery and Characterization|
Brian J. Parker and Thomas Preiss
|73||Chapter 5: Traditional Approaches to RNA Structure Analysis|
|93||Chapter 6: RNA Structure: Probing Biochemical Analyses|
Subash C.B. Gopinath
|111||Chapter 7: RNA Structural Analysis Based on Thermal Denaturation|
Carla A. Theimer, Nakesha L. Smith, and Khadijah Onanuga-Islam
|131||Chapter 8: Probing the Structural Basis of Retroviral RNA Functions via NMR Spectroscopy|
Blanton S. Tolbert, Carrie Rollins, Jeffrey D. Levengood, Le Luo, and Prashant Rajan
|153||Chapter 9: Probing the Folding and Structural Dynamics in RNAs by Single-Molecule Approaches|
Guangtao Song and Maumita Mandal
|185||Chapter 10: Application of Single-Molecule Fluorescence in RNA Biology|
Pan T.X. Li and Lori Goldner
|213||Chapter 11: Rational Design of RNA Nanoparticles and Nanoarrays|
|235||Chapter 12: Tailor-Made RNAs: From Self-Folding RNAs to Ribonucleoproteins|
|247||Chapter 13: Small RNA–Mediated Transcriptional Modulation|
Thomas C. Roberts and Matthew J. A. Wood
|287||Chapter 14: Small RNA Molecules in Antiviral Therapy|
Ye Qiu, Xin Ye, Maged Hemida, Mary Zhang, Paul Hanson, and Decheng Yang
|317||Chapter 15: Cell Specificity of siRNA as a Key for Therapeutic Applications|
Tobias G. Poehlmann, Juliane Reiche, Mirko Ludwig, and Rolf Guenther
|331||Chapter 16: Targeting Alternative Splicing in Human Genetic Disease|
Michael R. Ladomery
|359||Chapter 17: Messenger RNA Metal Sensing: Iron-Responsive Element (IRE)-mRNA Is a Metal-Sensitive Riboregulator|
Mateen A. Khan
|385||Chapter 18: RNA Information Gene Diseases: Nano-RNA-Based Medical Devices with Corporate Chemotherapy and Gene Therapy|
Yoichi Robertus Fujii
Advanced undergraduate- and graduate-level students in nanobiotechnology; researchers in RNA science, nanotechnology, biology, chemistry, and medicine, especially those with an interest in cancer therapy or drug delivery.
The characters you copied from the image are incorrect. Please try again.