Tissue and Organ Regeneration - Advances in Micro- and Nanotechnology
by Grace Lijie Zhang (The George Washington University, USA), Thomas Webster (Northeastern University, USA), Ali Khademhosseini (Harvard Medical School, USA)
Hardback 799 pages 2014-04-30 Print ISBN: 9789814411677 eBook ISBN: 9789814411684 DOI: 10.4032/9789814411684
List price : $169.95
“This practical tour de force will quickly bring you up to speed on the most recent tools and techniques for controlling cellular behavior. With contributions from internationally renowned authors, readers can explore a comprehensive collection of articles tailored for scientists, research engineers, and students to learn basic and advanced micro/nanotechnology protocols. The book helps professionals understand the many intricate steps involved in microenvironmental control in tissue engineering, focusing on state-of-the-art approaches for delivering soluble and substrate-based cues to cells. If you have an interest in tissue engineering or regenerative medicine, this book is a must-have!”
Prof. Jeffrey M. Karp - Brigham and Women's Hospital, USA
Tissue engineering aims to develop biological substitutes that restore, maintain, or improve damaged tissue and organ functionality. To date, there are two fundamental tissue engineering approaches for tissue and organ regeneration: stem cell–based regeneration and biomaterial-based regeneration. The challenge of existing stem cell–based techniques is that current therapies lack controlled environments that are crucial to regulate stem cell engraftment and differentiation in vivo, because stem cells are rather sensitive to even minute changes in their environment. Micro/nanotechnology hold great potential to control stem cell differentiation and fate in vivo.
This book presents the latest nano/microtechnologies used to manipulate stem cell behaviors, which is a critical area for regenerative medicine. Moreover, it covers and details cutting-edge research in nano/microfabrication techniques and biomaterials for various tissue/organ, such as bone, cartilage, craniofacial, osteochondral, muscle, bladder and cardiovascular tissue, etc., regenerations.
The contributors of this book are prominent authors that include Dr. Joseph P. Vacanti (Harvard Medical School, pioneer in tissue engineering); Dr. Anthony Atala (Wake Forest, chair of the Department of Urology, top researcher in organ regeneration); Dr. Kyriacos A. Athanasiou (UC Davis, chair of the Department of Biomedical Engineering and president of Biomedical Engineering Society 2003); Dr. Cato T. Laurencin (University of Connecticut, member of the National Academy of Engineering); Dr. Jennifer West (Duke University, former chair of the Department of Bioengineering at Rice University); and Gilda A. Barabino (Georgia Institute of Technology, President of Biomedical Engineering Society 2011).
About the Editors:
Prof. Lijie Grace Zhang is assistant professor in the Department of Mechanical and Aerospace Engineering and Department of Medicine at the George Washington University (GW), Washington D.C., USA. She is director of the Bioengineering Laboratory for Nanomedicine and Tissue Engineering at GW. She got her PhD in biomedical engineering from Brown University, Rhode Isalnd, and did her postdoctoral study at Rice University, Texas, and Harvard Medical School, Massachusetts, USA.
Prof. Ali Khademhosseini is associate professor at Harvard-MIT Division of Health Sciences and Technology (HST), Brigham and Women’s Hospital (BWH), and Harvard Medical School (HMS) as well as associate faculty at the Wyss Institute for Biologically Inspired Engineering, Massachusetts, USA. He is also junior principal investigator at Japan’s World Premier International—Advanced Institute for Materials Research (WPI-AIMR) at Tohoku University, where he directs a satellite laboratory.
Prof. Thomas J. Webster’s degrees are in chemical engineering from the University of Pittsburgh (B.S., 1995) and in biomedical engineering from Rensselaer Polytechnic Institute (M.S., 1997; Ph.D., 2000). He is currently the chair of the Department of Chemical Engineering at Northeastern University, Boston, USA. His research explores the use of nanotechnology in numerous applications.
|1||Chapter 1: Nano/Microfabrication Techniques for Tissue and Organ Regeneration|
Benjamin Holmes, Thomas J. Webster, and Lijie Grace Zhang
|37||Chapter 2: Three-Dimensional Micropatterning of Biomaterial Scaffolds for Tissue Engineering|
Joseph C. Hoffmann and Jennifer L. West
|75||Chapter 3: Nanobiotechnology and Biomaterials for Regenerative Medicine|
Nupura S. Bhise and Jordan J. Green
|105||Chapter 4: Micro- and Nanotechnology Engineering Strategies for Tissue Interface Regeneration and Repair|
Torri E. Rinker and Johnna S. Temenoff
|157||Chapter 5: Spatiotemporal Genetic Control of Cellular Systems|
Lauren R. Polstein and Charles A. Gersbach
|199||Chapter 6: Biomimetic Design of Extracellular Matrix-Like Substrate for Tissue Regeneration|
Chao Jia, Seyed Babak Mahjour, Lawrence Chan, Da-wei Hou, and Hongjun Wang
|231||Chapter 7: Degradable Elastomers for Tissue Regeneration|
G. Rajesh Krishnan, Michael J. Hill, and Debanjan Sarkar
|265||Chapter 8: Protein Engineering Strategies for Modular, Responsive, and Spatially Organized Biomaterials|
|295||Chapter 9: Design and Fabrication of Biomimetic Microvascular Architecture|
Thomas M. Cervantes and Joseph P. Vacanti
|335||Chapter 10: Tissue Engineering of Human Bladder|
|369||Chapter 11: The Self-Assembling Process of Articular Cartilage and Self-Organization in Tissue Engineering|
Pasha Hadidi, Rajalakshmanan Eswaramoorthy, Jerry C. Hu, and Kyriacos A. Athanasiou
|409||Chapter 12: Environmental Factors in Cartilage Tissue Engineering|
Yueh-Hsun Yang and Gilda A. Barabino
|455||Chapter 13: Bone Regenerative Engineering: The Influence of Micro- and Nano-Dimension|
Roshan James, Meng Deng, Sangamesh G. Kumbar, and Cato T. Laurencin
|495||Chapter 14: Stem Cells and Bone Regeneration|
Martin L. Decaris, Kaitlin C. Murphy, and J. Kent Leach
|535||Chapter 15: Notch Signaling Biomaterials and Tissue Regeneration|
Thanaphum Osathanon, Prasit Pavasant, and Cecilia Giachelli
|565||Chapter 16: Stem Cell-Based Dental, Oral, and Craniofacial Tissue Engineering|
Sahng G. Kim, Chang Hun Lee, Jian Zhou, Mo Chen, Ying Zheng, Mildred C. Embree, Kimi Kong, Karen Song, Susan Y. Fu, Shoko Cho, Nan Jiang, and Jeremy J. Mao
|589||Chapter 17: Engineering Functional Bone Grafts for Craniofacial Regeneration|
Pinar Yilgor Huri and Warren L. Grayson
|621||Chapter 18: Nanotechnology in Osteochondral Regeneration|
Nathan J. Castro, Joseph R. O’Brien, and Lijie Grace Zhang
|645||Chapter 19: Aortic Heart Valve Tissue Regeneration|
Bin Duan, Laura A. Hockaday, Kevin H. Kang, and Jonathan T. Butcher
|695||Chapter 20: Micro and Nanotechnology in Vascular Regeneration|
Vivian Lee and Guohao Dai
|725||Chapter 21: Micro- and Nanofabrication Approaches to Cardiac Tissue Engineering|
Nicole Trosper, Petra Kerscher, Jesse Macadangdang, Daniel Carson, Elizabeth Lipke, and Deok-Ho Kim
|755||Chapter 22: Engineering of Skeletal Muscle Regeneration: Principles, Current State, and Challenges|
Weining Bian, Mark Juhas, and Nenad Bursac
Advanced undergraduate and graduate students in the field of biomedical engineering, tissue engineering and regenerative medicine; biomedical researchers interested in tissue and organ regeneration.
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